If LOLs are in your DNA, you’ll love these gene-uinely funny biology jokes
20 Biology Jokes So Funny, They Cell Themselves
Updated on Jul. 10, 2025
Who says science can’t make you laugh? If the line “mitochondria is the powerhouse of the cell” is burned into your brain forever, congratulations—you’re biologically equipped for some goofy science jokes. And once you find out that the mushroom was so popular in college because he was a fun-gi, the biology jokes really start to cell themselves. Retell a few of these clever biology jokes at your next party, and you won’t just get laughs—you’ll sound brilliant while you’re at it.
Of course, we know that not everyone’s a pro at science humor, and that’s OK. But whether you’re into biology jokes, chemistry puns or just here for a laugh (even with a bachelor’s in history), science humor truly has something for everyone. If you do want to join the pun game, though, just brush up on your molecular wordplay. Until then, read on and enjoy some of the funniest biology jokes we naturally selected.
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Funniest biology jokes
- Why did the biologist break up with the physicist?
They had no chemistry.
- What did the cell exclaim when he ran into the table?
“Mitosis!”
- Why wouldn’t the scientist go into the haunted house?
He was too petrified.
- Why didn’t anyone want the biologist’s new book?
It was a hard cell.
- What does a biologist tell you when you have to give blood?
B positive!
- What happened to all of the bird viruses?
They flu away.
- What do you call it when your biology grade goes from an A to an F?
Biodegraded.
Corny biology jokes
- Why do biologists look forward to casual Fridays?
They’re allowed to wear genes to work.
- What do biologists post on Instagram?
Cell-fies.
- Why aren’t students allowed in the biology teachers’ lounge?
It’s for staph only.
- What do you call an organic compound with an attitude?
A-mean-o acid.
- Why do biologists like to travel?
It makes them more cultured.
- What do hipster biologists wear?
Skinny genes.
- Why did the woman break up with the biologist?
He was too cell-fish.
Dad biology jokes
- Why did the scuba diver fail biology?
He was below C level.
- How does a marine biologist end a conversation?
Sea you later!
- Why was the amoeba sad?
His parents just split.
- Why did the bacteria cross the microscope?
To get to the other slide.
- Why was the mushroom so popular?
He was a real fungi.
- What did the femur say to the patella?
I kneed you.
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Reader’s Digest has been telling jokes for more than 100 years, curated and reviewed over the last 20 years by Senior Features Editor Andy Simmons, a humor editor formerly of National Lampoon and the author of Now That’s Funny. We’ve earned prestigious ASME awards for our humor—including comical quips, pranks, puns, cartoons, one-liners, knock-knock jokes, riddles, memes, tweets and stories in laugh-out-loud magazine columns such as “Life in These United States,” “All in a Day’s Work,” “Laughter, the Best Medicine” and “Humor in Uniform,” as well as online collections such as short jokes, dad jokes and bad jokes so bad, they’re great. You can find a century of humor in our 2022 compendium, Reader’s Digest: Laughter, the Best Medicine. Read more about our team, our contributors and our editorial policies.
